Biopore sperm binding assay

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Pantke, J. Hyland, D. Galloway, D.

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Sequestration of free syntaxin impedes docking of the acrosome to the plasma membrane assessed by transmission electron microscopy. The implications of this study are twofold: our findings explain the fertility defect of hyh mice and indicate that assembly of SNAREs in trans complexes is essential for docking. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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In most mammalian species, the uterotubal junction acts as a selective entrance filter for motile sperm with superior morphology. Upon reaching the oviduct, sperm are trapped in the intraluminal mucus of the caudal isthmus, where they bind to the ciliated epithelial cells that line the duct. The binding event creates in the female a sperm reservoir with a number of functions: control of sperm transport to the site of fertilisation, selection of viable sperm, maintenance of sperm viability and modulation of capacitation to synchronise sperm fertilising ability with the time of ovulation reviewed recently by ScottRodriguez-Martinez et al.

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Year of fee payment : 4. Year of fee payment : 8. Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses.

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Leahy, J. Rickard and S. O2: Comparison of three variants of colloid centrifugation for sperm selection: sperm quality and blastocyst development in vitro.

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This application is a continuation of copending application Ser. The present invention relates to an evaluation process for assessing the fertility of avian and mammalian spermatozoa. Assisted reproductive technologies such as artificial insemination have been practiced commercially with livestock and horses for almost a century, and with poultry, humans and other species for almost a half century.

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Kind code of ref document : A2. USP true Integration of fluids and reagents into self-contained cartridges containing sensor elements. System and method for integrating fluids and reagents in self-contained cartridges containing sensor elements.

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The present invention relates to a method and device for the detection of analytes in a fluid. Although many sensors capable of high sensitivity and high selectivity detection have been fashioned for single analyte detection, only in a few selected cases have array sensors been prepared which display solution phase multi-analyte detection capabilities. The advantages of such array systems are their utility for the analysis of multiple analytes and their ability to be "trained" to respond to new stimuli.

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Background: The purpose of this study was to evaluate the prognostic effect of Hyaluronan Binding Assay HBA which has been used as a method of sperm selection for intracytoplasmic sperm injection procedure, on the outcome of intrauterine insemination IUI in couples with unexplained or mild male factor infertility. Methods: 77 infertile couples were enrolled in our study. HBA values and semen parameters were compared.

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