Neuroendocrine carcinoma of the breast

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Among the all-primary carcinomas of the breast, the incidence of mucinous colloid or gelatinous carcinomas of breast accounts for 1. It is a well-recognized type of infiltrating ductal carcinoma, occurring mainly in elderly women and carrying a good prognosis. The following is a case report of a 67 year old female having mucinous carcinoma with neuroendocrine differentiation subsequently confirmed by immunohistochemistry IHC.

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A year-old G2P1 female presented with a new palpable right breast lump, which she had noticed while breastfeeding. Her risks for breast cancer included a maternal grandmother who was diagnosed with breast cancer in her 50s and late childbearing at age On physical examination, she had a large palpable non-tender mass in the lower right breast.

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In most cases, breast neuroendocrine tumours are histologically and moderately well differentiated. Neuroendocrine breast tumours lack characteristic imaging patterns. The histopathological assessment of these tumours is difficult, and in most cases the correct diagnosis is made after proper examination of the postsurgical specimen.

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We present here a case of a year-old woman diagnosed with primary neuroendocrine carcinoma of the breast NECB. We discuss the importance of histological criteria for primary neuroendocrine mammary carcinoma, established by WHO in and After an overview of different cases of primary neuroendocrine carcinoma of the breast published in the literature, we present information about differential diagnosis, prognostic factors, and surgical and adjuvant treatment.

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Aim: Neuroendocrine type breast carcinomas are rarely observed. Most of these tumors are seen as cell-differentiated neuroendocrine breast carcinoma but with all this infrequency, there is also a rarer type which is called as pure neuroendocrine breast carcinoma. The common locations for neuroendocrine tumors are lung and gastrointestinal system stomach and pancreas.

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The authors present a case of a neuroendocrine carcinoma in an asymptomatic year-old woman, detected in routine breast screening. The lesion was visible at mammography as a well circumscribed, medium density nodule, with no associated microcalcifications, and at ultrasonography as a hypoechoic nodule, with irregular shape and ill-defined margins. Magnetic resonance imaging revealed findings consistent with malignancy. Neuroendocrine carcinomas are rare malignant tumors which, in most of cases, are located in the lungs and gastrointestinal tract.

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